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Generic drugs make up 90% of prescriptions but only 20% of spending - and that’s why they’re disappearing. Cheap prices, foreign factories, and broken incentives are causing critical drug shortages affecting millions.
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Ciclopirox is no longer just a nail fungus treatment. New research shows promise in cancer, antibiotic-resistant infections, and advanced topical delivery - making it one of the most surprising drug repurposing stories of 2025.
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States use Preferred Drug Lists, pharmacist substitution rules, and copay differences to push generic drug use. These policies save billions without compromising care - but unintended rebate rules are putting some generics at risk.
In my latest blog post, I discussed the crucial role of cycloserine in managing multidrug-resistant tuberculosis (MDR-TB). Cycloserine, an antibiotic, has become increasingly important in the treatment of MDR-TB, especially when other first-line medications are ineffective. This is because it targets the bacteria causing TB in a different way, thus overcoming resistance. However, it's essential to use cycloserine in combination with other antibiotics to ensure maximum effectiveness and minimize the risk of further resistance. Overall, cycloserine plays a vital role in the fight against MDR-TB, and ongoing research is crucial to optimize its use and develop new treatments.
Learn how the FDA ensures generic drugs are safe, effective, and affordable. Understand the approval process, why generics cost less, and what you need to know as a patient.