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Effective patent life for drugs is often just 10-13 years, not 20, because development and approval eat up half the patent term. Learn how patents, exclusivities, and legal tactics delay generic competition.
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Twenty-seven U.S. states have special rules restricting generic substitution for narrow therapeutic index (NTI) drugs like warfarin, levothyroxine, and lithium. These laws vary widely - from outright bans to dual consent requirements - creating a patchwork that affects patient safety, pharmacy workflows, and drug costs.
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